Document Details

Document Type : Article In Journal 
Document Title :
The Genetic Effect of the Combined Action of Vincristine and Fennel Plant Extract on the Germ Cells of Drosophilla melanogaster
التأثير الطفري للمعاملة المفردة والمشتركة لمستخلص نبات شمر وعقار الفينكريستين في حشرة الدروسوفيلا ميلانوجاستر
 
Subject : Biology 
Document Language : English 
Abstract : This study was designed to investigate the mutagenic potentiality of the anticancer drug vincristine and fennel plant extract on Drosophilla melanogaster using two test systems, the sex linked recessive lethal (SLRL) and estimating the activity of cholinesterase enzyme (ChE) in F1 and F2 bar eye females and F2 wild types males. A wild type Strain Oregon-R (or-R) male flies of D. melanogaster were treated on a medium containing a concentration of one of individually of the two agents, followed by combined treatment in an alternative way of fennel extract followed by vincristin, then vincristin followed by fennel extract and finally the two agents together. The results showed no significant increase in the percentage of the S.L.R.L in all stages of spermatogenesis in all treatments. Meanwhile, vincristine and fennel plant extract showed a genotoxic effects in the three categories of the two generations of S.L.R.L, F1 females heterozygous F2 bar eye females and F2 wild type males on the genetic background of ChE in all treatments. 
ISSN : 1012-1319 
Journal Name : Science Journal 
Volume : 20 
Issue Number : 1 
Publishing Year : 1429 AH
2008 AD 
Number Of Pages : 11 
Article Type : Article 
Added Date : Sunday, October 11, 2009 

Researchers

Researcher Name (Arabic)Researcher Name (English)Researcher TypeDr GradeEmail
ندى حسن التواني N. H. Al-TwanyResearcher  
إكرام صلاح الدين أحمد E. S. AhmedResearcher  
سهام عبدالله كرديS. A. KurdiResearcher  

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