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Document Type |
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Article In Journal |
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Document Title |
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Therapeutic Effects of Herbal Leaves Group (Green Tea & Sage) on Liver Cancer التأثيرات العلاجية لمجموعة الأوراق العشبية ( الشاي الأخضر والمريميية ) على سرطان الكبد |
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Subject |
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Biochemistry |
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Document Language |
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Arabic |
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Abstract |
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Tea is a beverage consumable next to water worldwide,
made from the leaves of theaceae family. Green tea (Camellia
Sinensis) tree, grown in China and India, contains good medical
properties. Name of salvia in Latin meaning treatment, made
from the leaves of labiatae family. Sage (Salvia officinalis) plant,
grown in general in mediterranean sea Country. In order to study
the therapeutic effects of leaves group, each one alone, on liver
cancer, 0.1 ml/100g of aflatoxin B1 (AFB1) was administrated intra-
peritoneal in male Wister Albino rats for a period of 10 days
to cause liver cancer. Green tea and sage, each one alone, were
given to rats for a period of 30 days. The animals were killed at
the end of the study and blood was tested for some biochemical
parameters including some key enzymes such as aspatate amino
transferase (AST), alanine amino transferase (ALT), gammaglutamyl
transferase (GGT), and other parameters which include
bilirubin, urea, uric acid, creatinine, cholesterol, triacylglycerols,
glucose, hemoglobin also part of the liver samples were taken to
determine the content of deoxyribonucleic acid (DNA), ribonucleic
acid (RNA) and total proteins, the other part was used for histological
examination. Those analyses were compared to control animals
that given AFB1 but not treated. The results from this study
demonstrated that green tea prevented the proliferation of liver
cancer at the initiating stage by inhibiting AFB1 effects on DNA
and regeneration of hepatocyte cells, in sage the effects were lesser
than green tea. |
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ISSN |
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1012-1319 |
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Journal Name |
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Science Journal |
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Volume |
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19 |
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Issue Number |
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1 |
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Publishing Year |
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1428 AH
2007 AD |
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Number Of Pages |
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30 |
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Article Type |
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Article |
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Added Date |
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Sunday, October 11, 2009 |
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