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Document Type |
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Article In Journal |
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Document Title |
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Type of Anti-Diabetic Treatment and Mortality Risk Factors in Type 2 Diabetics Attending Medical Out-Patient Clinic of a Teaching Hospital نوع العقاقير المستخدمة لعلاج مرضى السكري والعوامل المؤثرة على الوفاة لدى مرضى السكري في النوع الثاني الذين يراجعون عيادة الباطنة في مستشفلى تعليمي |
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Subject |
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Original Articles |
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Document Language |
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English |
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Abstract |
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To study the different types of anti-diabetic treatment
used in Type-2 diabetics attending King Abdulaziz University Hospital
out-patient medical clinic and to determine their mortality risk
factors, a random sample of 426 Type 2 diabetics was selected to participate
in the study. Demographic data were collected as well as
their nationality, duration of diabetes, degree of blood glucose control,
type of antidiabetic treatment (oral hypoglycemic agents and
their type, insulin or combined, presence of obesity, presence of hyperlipidemia,
presence of hypertension, presence of ischemic heart
disease, presence of renal failure, presence of stroke or transit ischemic
attack, smoking (active or passive), and mortality. The mean
age of the study group was 49 years with male:female ratio of 1.9:1.
The mean duration of diabetes was 11 years. Oral hypoglycemic
agents were the most frequently used antidiabetic treatment; 57%
versus 36% insulin and 7% combined oral hypoglycaemic and insulin.
Glibenclamide followed by metformin were the most common
used oral hypoglycemic agents: 57% and 51%, respectively, while
Repaglinide, rosiglitazone were used in 7% and 4%, respectively.
On multiple regression analysis after adjustment to all factors and
sex; presence of ischemic heart disease, hypertension, hyperlipidemia
and poor glycemic control were the most significant risk factors associated
with mortality; O.R. 7.3, 2.07, 2.99, 2.76 (95% C.I. 2.1 -26.4, 1.15 - 3.71, 1.70 - 5.2, 1.1 - 6.7), and p value 0.002, 0.01, 0.001,
0.02, respectively. These are under use of new generations of oral hypoglycemic
agents and insulin. Actions should be taken towards this.
Free supply of medications might be of help. |
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ISSN |
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1319-1004 |
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Journal Name |
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Medical Science Journal |
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Volume |
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12 |
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Issue Number |
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1 |
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Publishing Year |
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1425-1426 AH
2005 AD |
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Number Of Pages |
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10 |
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Article Type |
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Article |
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Added Date |
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Sunday, October 11, 2009 |
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