Document Details

Document Type : Article In Journal 
Document Title :
Chemoembolization in Metastatic Liver Neoplasms: KADR Experience
المعالجة الكيميائية لسرطانة الكبد الثانوية لأورام أولية متعددة غير قطوعة
 
Subject : Original Articles 
Document Language : English 
Abstract : Objective To assess the results of chemoembolization in this pilot study for patients with unresetable metastatic liver neoplasms. Methods: Patients with unresectable liver metastases secondary to different primary tumors who did not have decompesated liver disease underwent selective intra-arterial chemotherapy consisting of 5-flourouracil, adriamycin and cisplatin followed by embolization of the fee4ing artery using Poly Vinyl Alcohol Particles (PVAP). Courses of treatment were given every four to six weeks for a minimum of three courses. Results: Eight patients with bilateral multiple or diffuse liver metastasis underwent chemoembolization. Five oUt of eight patients had good palliation of symptoms and improvement in their quality of life. Their average duration of palliation was 7.2 months. Median survival for all patients was seven months. Seven patients died within the first year from a diagnosis of liver metastasis. The last patient with carcinoid syndrome is still alive 36 months after diagnosis. Conclusion: Selective intra-arterial chemotherapy followed by embolizatiop in this pilot study with unresectable liver metastases gives palliation of symptoms and improvement in the quality of life for almost half of our patients but for a short duratiun. Patients with neuroendocrine tumors may have longer duration of palliation and survival. Further randomized trials with a higher numberof patients would be worthwhile pursuing.  
ISSN : 1319-1004 
Journal Name : Medical Science Journal 
Volume : 7 
Issue Number : 1 
Publishing Year : 1419 AH
1999 AD 
Number Of Pages : 5 
Article Type : Article 
Added Date : Sunday, October 11, 2009 

Researchers

Researcher Name (Arabic)Researcher Name (English)Researcher TypeDr GradeEmail
محمود الأحول MAHMOUD S. AL-AHWALResearcher  
محمد رواس MOHAMMAD M. RAWASResearcher  
هشام أكبر HISHAM O. AKBARResearcher  

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